Missing Genes Linked to Obesity
February 4th, 2010 by Penny Hagerman
For years now, we’ve all heard the “nature vs nuture” argument as it relates to obesity, and wonder whether environment or genetics plays a larger role where weight is concerned.
Some say it’s all about environment—and we should be teaching our kids healthy eating habits from the time they’re young to prevent lifetime weight gain. Proponents of the nurture theory often place the blame on the shoulders of the overweight, saying they’re fat because they’re lazy, eat too much or lead a sedentary lifestyle.
Others point to genetics, claiming that, no matter what they eat or how much they exercise, they’re destined to be fat, just like their parents or other family members. No matter how hard they try, they just can’t get the extra weight off, and often put themselves at further health risk by resorting to desperate measures in order to lose the additional weight.
Either way, obesity can lead to many health problems that are difficult to overcome and can make getting and staying insured difficult.
In fact, those who are overweight usually pay at least 15 percent more for health insurance than individuals of normal weight—if they can get insured at all.
But a new report published today in the journal Nature now indicates that genetics may play a larger role in obesity than any of us previously realized.
In a recent European study, scientists found a rare genetic abnormality that is linked to both severe obesity and learning disabilities: the absence of 30 genes that reportedly virtually guarantee that a person will become obese.
What are the missing genes doing to cause obesity? No one is really sure, but experts speculate their absence may cause the production of an enzyme or protein that keeps the overweight from being able to burn energy efficiently.
With the genes necessary for regulating the body’s calorie consumption and energy burning process absent, obesity appears to result 100 percent of the time.
Though balancing caloric intake with expended energy is often the key to maintaining a healthy weight, the bodies of the obese don’t always function normally. Instead, they often “extract calories from food more effectively and may not be burning energy as efficiently as others,” says Dr. Stuart Weiss, an assistant clinical professor at NYU Langone Medical Center, in today’s Yahoo news article on the subject.
Maybe in the future, we’ll all undergo genetic tests to see if we’re missing any genes and, if so, what can be done to counteract the effects of their absence. Who knows, maybe scientists will find a cure for obesity—or figure out a way to overcome the effect of genetics on our bodies.
Meanwhile, it looks like science is proving that nature plays a much bigger role than previously thought.
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